Rifamycin
Group of antibiotics / From Wikipedia, the free encyclopedia
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The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis rifamycinica or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex (MAC) infections.
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Trade names | Aemcolo |
AHFS/Drugs.com | Monograph |
MedlinePlus | a619010 |
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Routes of administration | By mouth |
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Formula | C37H47NO12 |
Molar mass | 697.778 g·mol−1 |
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The rifamycin group includes the "classic" rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, rifapentine, rifalazil and rifaximin. Rifamycin, sold under the trade name Aemcolo, is approved in the United States for treatment of travelers' diarrhea in some circumstances.[1][2][3]
The name "rifamycin" (originally "rifomycin") was derived from the 1955 French film Rififi.[4]: S402