Ubiquinol
Chemical compound / From Wikipedia, the free encyclopedia
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A ubiquinol is an electron-rich (reduced) form of coenzyme Q (ubiquinone). The term most often refers to ubiquinol-10, with a 10-unit tail most commonly found in humans.
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IUPAC name
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methyl-benzene-1,4-diol | |
Other names
Reduced CoQ10, unoxidized CoQ10, CoQ10H2, or dihydroquinone | |
Identifiers | |
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3D model (JSmol) |
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ChemSpider |
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MeSH | C003741 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C59H92O4 | |
Molar mass | 865.381 g·mol−1 |
Appearance | off-white powder |
Melting point | 45.6 °C (114.1 °F; 318.8 K) |
practically insoluble in water | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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The natural ubiquinol form of coenzyme Q is 2,3-dimethoxy-5-methyl-6-poly prenyl-1,4-benzoquinol, where the polyprenylated side-chain is 9-10 units long in mammals. Coenzyme Q10 (CoQ10) exists in three redox states, fully oxidized (ubiquinone), partially reduced (semiquinone or ubisemiquinone), and fully reduced (ubiquinol). The redox functions of ubiquinol in cellular energy production and antioxidant protection are based on the ability to exchange two electrons in a redox cycle between ubiquinol (reduced) and the ubiquinone (oxidized) form.[1][2]