7α-Methylestradiol
Chemical compound / From Wikipedia, the free encyclopedia
Not to be confused with Methylestradiol.
7α-Methylestradiol (7α-Me-E2), also known as 7α-methylestra-1,3,5(10)-triene-3,17β-diol, is a synthetic estrogen and an active metabolite of the androgen/anabolic steroids trestolone/Methandienone.[1][2][3] It is considered to be responsible for the estrogenic activity of trestolone.[2][3] The compound shows about the same affinity for the estrogen receptor as estradiol.[1]
More information Compound, PRTooltip Progesterone receptor ...
Compound | PRTooltip Progesterone receptor | ARTooltip Androgen receptor | ERTooltip Estrogen receptor | GRTooltip Glucocorticoid receptor | MRTooltip Mineralocorticoid receptor | SHBGTooltip Sex hormone-binding globulin | CBGTooltip Corticosteroid binding globulin | |
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Estradiol | 2.6 | 7.9 | 100 | 0.6 | 0.13 | 8.7 | <0.1 | |
7α-Methylestradiol | 1–3 | 15–25 | 101 | <1 | <1 | ? | ? | |
Trestolone | 50–75 | 100–125 | ? | <1 | ? | ? | ? | |
Values are percentages (%). Reference ligands (100%) were progesterone for the PRTooltip progesterone receptor, testosterone for the ARTooltip androgen receptor, E2 for the ERTooltip estrogen receptor, DEXATooltip dexamethasone for the GRTooltip glucocorticoid receptor, aldosterone for the MRTooltip mineralocorticoid receptor, DHTTooltip dihydrotestosterone for SHBGTooltip sex hormone-binding globulin, and cortisol for CBGTooltip Corticosteroid-binding globulin. |
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Quick Facts Clinical data, Other names ...
Clinical data | |
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Other names | 7α-Methyl-E2; 7α-Me-E2; 7α-Methylestra-1,3,5(10)-triene-3,17β-diol |
Drug class | Estrogen |
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Chemical and physical data | |
Formula | C19H26O2 |
Molar mass | 286.415 g·mol−1 |
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